Saw this via foflist. Are you talking about the new Windows security patches? It's been causing multiple problems, including conflicting with HP software and some graphics drivers--one of the symptoms is probs with IE. I don't have the answer for you, but these links may help:

http://www.informationweek.com/windows/showArticle.jhtml?articleID=185303839

http://www.pcworld.com/news/article/0,aid,125420,00.asp